The University of Arizona

College of Agriculture and Life Sciences

Natural Products Center

The Natural Products Center (NPC) was set up in 1996 in the former Bioscience Research Facility on Valencia Road. Today NPC is engaged in research on anticancer, anti-HIV, anti-infective, and anti-inflammatory drug discovery from Sonoran desert plants and their associated microorganisms, genetic investigation of natural product biosynthesis in selected microorganisms, commercialization of Hesperaloe fiber, and development of alternate agricultural systems. Most of these projects are targeted for improving the longevity of agriculture in Arizona, the Southwest, and semiarid lands throughout the world and to understand the complex ecology of arid land ecosystems.

 

Equipment:

  • Chromatography Equipment (for Separation of Natural Products)
    • Analytical High Pressure Liquid Chromatograph (HPLC) equipped with an auto-sampler, Photo Diode Array (PDA) and Evaporative Light Scattering (ELS) detectors
    • Preparative High Pressure Liquid Chromatograph (HPLC) equipped with a Photo Diode Array (PDA) detector
  • Spectroscopic Equipment (for Structure Elucidation of Natural Products)
    • Nuclear Magnetic Resonance (NMR) (400 MHz) spectrometer equipped with proton, carbon, and all two-dimensional spectral measurement facilities
    • Liquid Chromatography-Mass Spectrometry (LC-MS) System equipped with an auto-sampler
    • Fourier Transform Infra-red (FT-IR) Spectrometer
    • Ultraviolet (UV) Spectrophotometer
  • Equipment for Biological Work
    • Flow Cytometer
    • Fluorescence Microscope equipped with a Digital Camera
    • Gel Electrophoresis and Documentation Systems
  • Equipment for Microbiological Work
    • Large Orbital Shaker Incubators
    • Modular Benchtop 14 L Fermenter (equipped with computer to add acid/base and anti-foam)